SCHEMBL8401064

SCHEMBL8401064

C=C(C(F)CCCCC)C(F)CCCCC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.56
LMNA P02545 1/20 0.41
OPRM1 P35372 1/20 0.39
FDPS P14324 4/20 0.38
GPR84 Q9NQS5 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
CA1 P00915 1/20 0.37
CES2 O00748 1/20 0.37
TP53 P04637 1/20 0.35
LAP3 P28838 1/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3746097 0.81 MAPT (0.34) MAPTFDPS
SCHEMBL27933351 0.79 MAPT (0.55) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL960629 0.77 MAPT (0.58) MAPTLMNAOPRM1FDPSGPR84
SCHEMBL9017852 0.76 MAPT (0.47) MAPTLMNAOPRM1FDPSGPR84
SCHEMBL472207 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL472166 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL4834358 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL9468203 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL1266499 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1
SCHEMBL472200 0.75 MAPT (0.61) MAPTLMNAFDPSGPR84SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618795-B1 PREPARATIONS CONTAINING A FLUOROCARBON EMULSION AND USABLE AS COSMETICS OR DERMATICS LANCASTER GROUP GMBH (DE) 1999-06-09 EP disclosed
US-5667772-A OXYGEN TO THE SKIN LANCASTER GROUP AG (DE) 1997-09-16 US disclosed