Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | KDM5C | P41229 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.56 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93265 | 0.95 | KDM4E (0.54) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL7227745 | 0.93 | KMT2A (0.56) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29282082 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28718365 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29586686 | 0.93 | HAO1 (0.54) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29046835 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29053209 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL4262073 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29035555 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL9342282 | 0.93 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859011-A | Dihydropyridine derivatives as bradykinin antagonist | PFIZER INC. (US) | 1999-01-12 | — | — | US | disclosed |