SCHEMBL8401100

SCHEMBL8401100

COCOCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
IDO1 P14902 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TAAR1 Q96RJ0 3/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
ATM Q13315 1/20 0.40
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30068495 0.88 KDM4E (0.41) CA1CA2CA9IDO1NPC1
SCHEMBL12815699 0.84 CA1 (0.47) CA1CA2CA9IDO1NPC1
SCHEMBL12847298 0.83 KDM4E (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL16594059 0.83 KDM4E (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL16594478 0.83 KDM4E (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL16594609 0.83 KDM4E (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL16594831 0.83 KDM4E (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL58391 0.81 KDM4E (0.49) CA1CA2CA9IDO1NPC1
SCHEMBL198134 0.81 TSHR (0.52) CA1CA2CA9IDO1NPC1
SCHEMBL15114792 0.81 KCNH2 (0.50) IDO1ALOX15TAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111601709-B Functional component 株式会社木本 2023-09-05 CN disclosed
CN-103479654-B Small molecule as the boracic of anti-inflammatory agent 安纳考尔医药公司 2018-02-09 CN disclosed
CN-106008583-A BORON-CONTAINING SMALL MOLECULES 安纳考尔医药公司 2016-10-12 CN disclosed
CN-106008571-A Boron-containing small molecules 安纳考尔医药公司 2016-10-12 CN disclosed
CN-105949230-A BORON-CONTAINING SMALL MOLECULES 安纳考尔医药公司 2016-09-21 CN disclosed
CN-102532180-B The little molecule of boracic 安纳考尔医药公司 2016-06-29 CN disclosed
US-20130184462-A1 METHOD FOR PREDICTING AND MODELING ANTI-PSYCHOTIC ACTIVITY USING VIRTUAL SCREENING MODEL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-07-18 US disclosed
US-5874097-A ANALYZING AIR SAMPLES NEAR OR IN BUILDINGS FOR THE PRESENCE OF A REPORTER MOLECULE, PREFERABLY NAPHTHALENE, TO INDICATE THE PRESENCE OF A TERMITE NEST BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 1999-02-23 US disclosed
US-5700938-A Intermediates for imidazopyridine derivatives EISAI CO., LTD. (JP) 1997-12-23 US disclosed
US-5618969-A Intermediates for imidazopyridines EISAI CO., LTD. (JP) 1997-04-08 US disclosed
US-5608068-A Process for the preparation of imidazopyridine derivatives and intermediates EISAI CO., LTD. (JP) 1997-03-04 US disclosed
US-5587504-A Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates EISAI CO., LTD. (JP) 1996-12-24 US disclosed
US-5583229-A Process for the preparation of imidazopyridine derivatives EISAI CO., LTD. (JP) 1996-12-10 US disclosed
US-5559236-A Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists EISAI CO., LTD. (JP) 1996-09-24 US disclosed
US-5557002-A Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists EISAI CO., LTD. (JP) 1996-09-17 US disclosed
US-5554757-A Process for the preparation of imidazopyridine derivatives, and intermediates therefore EISAI CO., LTD. (JP) 1996-09-10 US disclosed
EP-0627433-A1 PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE Eisai Co., Ltd. (JP) 1994-12-07 EP disclosed