Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235042 | 0.75 | CYP1A2 (0.38) | MEN1KMT2AMAPT | |
| SCHEMBL1120018 | 0.71 | — | — | |
| SCHEMBL2418026 | 0.71 | — | — | |
| Methane SCHEMBL28737048 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| Ammonia Solution, Strong SCHEMBL28139008 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| Charcoal, Activated SCHEMBL29882480 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| SCHEMBL28363865 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| Hydrochloric Acid SCHEMBL6951148 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| SCHEMBL29921145 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT | |
| SCHEMBL27590220 | 0.70 | MEN1 (0.36) | MEN1KMT2ASIRT2SIRT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |