Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.54 |
| ▸ | CAPNS1 | P04632 | 4/20 | 0.53 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.44 |
| ▸ | CASP3 | P42574 | 6/20 | 0.44 |
| ▸ | CASP6 | P55212 | 5/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 5/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404230 | 1.00 | CAPN1 (0.54) | CAPN1CAPNS1LARS1CASP1CASP3 | |
| SCHEMBL8404242 | 0.90 | CAPN1 (0.54) | CAPN1CAPNS1LARS1KMT2AMEN1 | |
| SCHEMBL8404247 | 0.90 | CAPN1 (0.54) | CAPN1CAPNS1LARS1KMT2AMEN1 | |
| SCHEMBL8403869 | 0.88 | CAPN1 (0.50) | CAPN1CAPNS1KMT2AMEN1 | |
| SCHEMBL8403866 | 0.88 | CAPN1 (0.50) | CAPN1CAPNS1KMT2AMEN1 | |
| SCHEMBL8810081 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1KMT2AMEN1 | |
| SCHEMBL8810089 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1KMT2AMEN1 | |
| SCHEMBL8407935 | 0.87 | CAPN1 (0.55) | CAPN1CAPNS1LARS1 | |
| SCHEMBL8407939 | 0.87 | CAPN1 (0.55) | CAPN1CAPNS1LARS1 | |
| SCHEMBL8406511 | 0.86 | CAPN1 (0.49) | CAPN1CAPNS1KMT2AMEN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |