Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408035 | 1.00 | CAPN1 (0.38) | CAPN1CAPNS1EPHX1ACHESMN1; SMN2 | |
| SCHEMBL8404294 | 1.00 | CAPN1 (0.38) | CAPN1CAPNS1EPHX1ACHESMN1; SMN2 | |
| SCHEMBL8407590 | 0.86 | EPHX1 (0.37) | CAPN1EPHX1ACHESMN1; SMN2GAA | |
| SCHEMBL8408073 | 0.86 | EPHX1 (0.37) | CAPN1EPHX1ACHESMN1; SMN2GAA | |
| SCHEMBL8407659 | 0.86 | EPHX1 (0.37) | CAPN1EPHX1ACHESMN1; SMN2GAA | |
| SCHEMBL8404239 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404293 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404243 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8408037 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404295 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | claimed |
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |