⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42294 | 1.00 | — | — | |
| SCHEMBL524531 | 1.00 | — | — | |
| SCHEMBL37585 | 1.00 | — | — | |
| SCHEMBL42873 | 1.00 | — | — | |
| SCHEMBL12559536 | 1.00 | — | — | |
| SCHEMBL29017454 | 0.95 | — | — | |
| SCHEMBL9652821 | 0.95 | — | — | |
| SCHEMBL18526909 | 0.95 | TSHR (0.50) | — | |
| SCHEMBL29140447 | 0.95 | TSHR (0.50) | — | |
| SCHEMBL7095654 | 0.95 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101550128-A | Axial chirality diamine compound induced by central chirality and synthetic method | CHUNJIANG WANG (CN) | 2009-10-07 | — | — | CN | claimed |
| US-12121880-B2 | Catalyst component for olefin polymerization, preparation method thereof, and catalyst including same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2024-10-22 | — | — | US | disclosed |
| CN-116947925-A | Bridged biphenyl monophosphine ligand containing benzofuran structure, and preparation method and application thereof | 中山大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113004341-B | PNO ligand containing facial chiral ferrocene and axial chiral diphenol and application thereof | 洛阳师范学院 | 2023-08-01 | — | — | CN | disclosed |
| CN-111499538-B | Preparation method of (2S, 3R) -2-acylaminomethyl-3-hydroxybutyrate | 南方科技大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-115651016-A | Chiral diphosphine ligand with alkyl skeleton and preparation method thereof | 中国科学技术大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113004341-A | PNO ligand containing chiral ferrocene and axial chiral biphenol and application thereof | 洛阳师范学院 | 2021-06-22 | — | — | CN | disclosed |
| CN-110511303-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-110511302-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-110511301-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2020-10-20 | — | — | CN | disclosed |
| WO-2016003880-A1 | ETHYLENE-BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016003879-A1 | PROCESS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016003878-A1 | CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| CN-102341501-B | Method for stereoselectively and enzymatically reducing keto compounds | IEP GMBH | 2015-07-08 | — | — | CN | disclosed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | disclosed |
| US-8143432-B2 | Process for regioselective mono-tosylation of diols | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-03-27 | — | — | US | disclosed |
| CN-102341501-A | Method for stereoselectively and enzymatically reducing keto compounds | IEP GMBH | 2012-02-01 | — | — | CN | disclosed |
| US-20100016623-A1 | PROCESS FOR REGIOSELECTIVE MONO-TOSYLATION OF DIOLS | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-21 | — | — | US | disclosed |
| CN-101550128-A | Axial chirality diamine compound induced by central chirality and synthetic method | CHUNJIANG WANG (CN) | 2009-10-07 | — | — | CN | disclosed |
| US-4273933-A | HYDROGENATION WITH NICKEL CATALYST | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 1981-06-16 | — | — | US | disclosed |