Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405927 | 0.85 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL394308 | 0.84 | CYP11B1 (0.83) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL3092795 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL24733003 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL12299569 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL10997898 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL8405395 | 0.77 | CYP11B1 (0.44) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL17289985 | 0.77 | CYP11B1 (0.66) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL8403785 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| Bromide SCHEMBL10944834 | 0.76 | CYP11B1 (0.69) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696268-A | REACTING N-ACYLAMINO ACID DERIVATIVE WITH OPTICALLY ACTIVE ENAMINE DERIVATIVE, REACTING PRODUCT WITH AMMONIA OR AMMONIUM SALT | FUJIREBIO INC. (JP) | 1997-12-09 | — | — | US | claimed |
| US-5859244-A | EXHIBIT VASODILATING ACTIVITY BASED ON CALCIUM ANTAGONISM AND PLATELET-ACTIVATING FACTOR ANTAGONISM | FUJIREBIO, INC. (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5763614-A | VASODILATION BASED ON CALCIUM ANTAGONISM AND PAF ANTAGONISM | FUJIREBIO INC. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5696268-A | REACTING N-ACYLAMINO ACID DERIVATIVE WITH OPTICALLY ACTIVE ENAMINE DERIVATIVE, REACTING PRODUCT WITH AMMONIA OR AMMONIUM SALT | FUJIREBIO INC. (JP) | 1997-12-09 | — | — | US | disclosed |