Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.92 |
| ▸ | LMNA | P02545 | 4/20 | 0.92 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.92 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.92 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.71 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.71 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 6/20 | 0.67 |
| ▸ | PPARD | Q03181 | 6/20 | 0.67 |
| ▸ | PPARA | Q07869 | 6/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TLR2 | O60603 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelic Acid SCHEMBL100415 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL3852958 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL20594219 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Succinic Acid SCHEMBL28346539 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL10456758 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Succinic Acid SCHEMBL28059863 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL5800699 | 1.00 | TSHR (0.92) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL28812368 | 0.96 | TSHR (0.86) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL28069641 | 0.96 | TSHR (0.86) | TSHRLMNANFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL28269347 | 0.96 | TSHR (0.86) | TSHRLMNANFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208787-A1 | AQUEOUS PIGMENT DISPERSION, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, INK COMPOSITION, INK COMPOSITION FOR INKJET RECORDING, AND INKJET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2018-07-26 | — | — | US | disclosed |
| US-20170335054-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND PROCESS OF MANUFACTURING THEREOF | ESTER INDUSTRIES LIMITED (IN) | 2017-11-23 | — | — | US | disclosed |
| EP-3221400-A2 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND PROCESS OF MANUFACTURING THEREOF | Ester Industries Limited (IN) | 2017-09-27 | — | — | EP | disclosed |
| CN-105324108-A | Composition for treating complications of aneurysmal subarachnoid hemorrhage and application thereof | EDGE THERAPEUTICS INC | 2016-02-10 | — | — | CN | disclosed |
| EP-2699485-A1 | CELLULOSIC BARRIER PACKAGING MATERIAL | BASF SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143323-A1 | CELLULOSIC BARRIER PACKAGING MATERIAL | BASF SE (DE) | 2012-10-26 | — | — | WO | disclosed |
| EP-0927019-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998048768-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |