SCHEMBL840602

SCHEMBL840602

Cc1cc2c3ccccc3c3ncc(Br)n3c2cc1C

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 2/20 0.40
PDE1A P54750 1/20 0.34
PDE1B Q01064 1/20 0.34
PDE3B Q13370 1/20 0.34
PDE1C Q14123 1/20 0.34
PDE3A Q14432 1/20 0.34
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.31
LMNA P02545 2/20 0.31
PTGER4 P35408 2/20 0.31
ALDH1A1 P00352 2/20 0.30
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
CHUK O15111 1/20 0.30
CHEK1 O14757 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840967 0.84 IKBKB (0.48) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL29516462 0.80 PDE1A (0.39) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL17557189 0.80 PDE1A (0.39) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL840110 0.78 WEE1 (0.32) MAPTALDH1A1MEN1KMT2A
SCHEMBL17557176 0.78 IKBKB (0.36) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL29994228 0.78 IKBKB (0.36) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL12145249 0.78 PDE1A (0.37) IKBKBPDE1APDE1BPDE3BPDE1C
SCHEMBL841547 0.76
SCHEMBL839838 0.75 PDE2A (0.33) LMNAALDH1A1KMT2A
SCHEMBL841028 0.74 GSK3B (0.33) MAPTCYP1A2LMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-2217827-B1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORP (US) 2020-06-03 EP disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
EP-1490427-A1 AMBIENT CURED COATINGS AND COATED RUBBER PRODUCTS THEREFROM Lord Corporation (US) 2004-12-29 EP disclosed
EP-1483348-A1 FLEXIBLE COATINGS FOR ELASTOMER SUBSTRATES Lord Corporation (US) 2004-12-08 EP disclosed
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US disclosed
WO-2004033573-A1 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2004-04-22 WO disclosed
US-20040068036-A1 Flexible emissive coatings for elastomer substrates LORD CORPORATION 2004-04-08 US disclosed
WO-2004011536-A1 AMBIENT CURED COATINGS AND COATED RUBBER PRODUCTS THEREFROM LORD CORPORATION (US) 2004-02-05 WO disclosed
US-20040018312-A1 Ambient cured coatings and coated rubber products therefrom LORD CORPORATION 2004-01-29 US disclosed
WO-2003076537-A1 FLEXIBLE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2003-09-18 WO disclosed
WO-2003048261-A1 ROOM TEMPERATURE CURABLE FLUOROPOLYMER COATING LORD CORPORATION (US) 2003-06-12 WO disclosed
US-20030104213-A1 Room temperature curable fluoropolymer coating LORD CORPORATION 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 IKBKB 4355/4885PDE1A 3118/4885PDE1B 4046/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 IKBKB 4277/4885PDE1A 4307/4885PDE1B 4001/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 IKBKB 4355/4885PDE1A 3118/4885PDE1B 4046/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 IKBKB 4355/4885PDE1A 3118/4885PDE1B 4046/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 IKBKB 4277/4885PDE1A 4307/4885PDE1B 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.