Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406646 | 0.94 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL8405405 | 0.89 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8401657 | 0.82 | CHRM1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL8405871 | 0.80 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL8401885 | 0.77 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL8405801 | 0.76 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL7477838 | 0.73 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8406017 | 0.72 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL9703172 | 0.70 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL9703187 | 0.70 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994373-A | COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS | NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) | 1999-11-30 | — | — | US | disclosed |