Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11356813 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL9168536 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL10556308 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL11096936 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL10345757 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL10346269 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL2944428 | 0.87 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL18868401 | 0.81 | ELANE (0.38) | ELANECTSLCTSKCTSSCTSB | |
| SCHEMBL10674650 | 0.81 | GLA (0.49) | ELANECTSLCTSKGLAIDO1 | |
| SCHEMBL10345690 | 0.81 | GLA (0.49) | ELANECTSLCTSKGLAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998612-A | Antibiotic synthesis | MERCK SHARP & DOHME CORP. | 1999-12-07 | — | — | US | disclosed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | disclosed |