Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 6/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550539 | 1.00 | KDM4E (0.67) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7552078 | 1.00 | KDM4E (0.67) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL8407786 | 1.00 | KDM4E (0.67) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7557172 | 0.99 | KDM4E (0.69) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL8412266 | 0.99 | KDM4E (0.69) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL8410600 | 0.99 | KDM4E (0.69) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7553841 | 0.99 | KDM4E (0.69) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7558098 | 0.94 | KDM4E (0.60) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL8409662 | 0.94 | KDM4E (0.60) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7550833 | 0.94 | KDM4E (0.60) | KDM4EKMT2AGAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965761-A | CROSSLINKABLE SILANE DERIVAATIVES HAVING A 3-ARYLACRYLIC ACID OR-ACRYLAMIDE GROUP FOR ORIENTING LAYER AND FOR NONSTRUCTURED AND STRUCTURED OPTICAL ELEMENTS AND MULTILAYER SYSTEMS; PHOTOSTABILITY; CONTRAST; RESOLUTION | ROLIC AG (CH) | 1999-10-12 | — | — | US | disclosed |