Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 11/20 | 0.51 |
| ▸ | CAPNS1 | P04632 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | CASP6 | P55212 | 3/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408055 | 1.00 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8403841 | 1.00 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8407885 | 1.00 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8403838 | 1.00 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8407887 | 1.00 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8404243 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8408037 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404295 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404239 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8404293 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | claimed |
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |