Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409409 | 0.95 | KDM4E (0.37) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8409215 | 0.92 | KDM4E (0.41) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8409064 | 0.90 | KDM4E (0.34) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8409029 | 0.88 | KDM4E (0.39) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8405428 | 0.88 | KDM4E (0.39) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8555058 | 0.87 | KDM4E (0.40) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7979192 | 0.87 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8405628 | 0.87 | HTT (0.38) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8405318 | 0.87 | KDM4E (0.37) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8408748 | 0.87 | KDM4E (0.37) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |