Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL580470 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Nonanoate SCHEMBL29370695 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Dodecanoate SCHEMBL19253062 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Palmitic Acid SCHEMBL10396224 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Octanoic Acid SCHEMBL2761867 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Myristic Acid SCHEMBL8588822 | 1.00 | FABP3 (0.55) | FABP3CA1BBOX1CES2CES1 | |
| Stearic Acid SCHEMBL3459529 | 0.98 | FABP3 (0.53) | FABP3CA1BBOX1CES2CES1 | |
| Myristic Acid SCHEMBL5317287 | 0.98 | FABP3 (0.53) | FABP3CA1BBOX1CES2CES1 | |
| Dodecanoate SCHEMBL5320074 | 0.98 | FABP3 (0.53) | FABP3CA1BBOX1CES2CES1 | |
| Decanoic Acid SCHEMBL5318916 | 0.98 | FABP3 (0.53) | FABP3CA1BBOX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023174433-A1 | SOLID, SEMISOLID, OR LIQUID COMPOSITIONS FOR AUGMENTING THE STABILITY, PERMEABILITY AND BIOAVAILABILITY OF ACTIVE PHARMACEUTICAL SUBSTANCES | Smart Pharmaceutical (Suzhou) Co., Ltd. (CN) | 2023-09-21 | — | — | WO | claimed |
| WO-2021231566-A1 | THE USE OF CHOLINE SUPPLEMENTATION AS THERAPY FOR APOE4-RELATED DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-11-18 | — | — | WO | claimed |
| US-20210353566-A1 | THE USE OF CHOLINE SUPPLEMENTATION AS THERAPY FOR APOE4-RELATED DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-11-18 | — | — | US | claimed |
| US-10736912-B2 | Compositions containing PUFA and/or uridine and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-11 | — | — | US | claimed |
| CN-105916969-B | Removal of free fatty acids from glyceride oils | 贝尔法斯特女王大学 | 2020-03-20 | — | — | CN | claimed |
| US-20190167705-A1 | COMPOSITIONS CONTAINING PUFA AND-OR URIDINE AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | claimed |
| EP-3074493-B1 | REMOVAL OF FREE FATTY ACIDS FROM GLYCERIDE OILS | UNIV BELFAST (GB) | 2019-01-09 | — | — | EP | claimed |
| US-10086009-B2 | Compositions containing pufa and/or uridine and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGIES (US) | 2018-10-02 | — | — | US | claimed |
| US-20180187122-A1 | REMOVAL OF FREE FATTY ACIDS FROM GLYCERIDE OILS | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-07-05 | — | — | US | claimed |
| CN-108138080-A | Free fatty is removed from glyceride oil | 英国贝尔法斯特女王大学 | 2018-06-08 | — | — | CN | claimed |
| CN-101415328-A | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-04-22 | — | — | CN | claimed |
| EP-1986662-A2 | METHODS AND COMPOSITIONS FOR AMELIORATING OR INHIBITING DECLINE IN MEMORY OR INTELLIGENCE OR IMPROVING SAME | Massachusetts Institute of Technology (MIT) (US) | 2008-11-05 | — | — | EP | claimed |
| EP-1870103-A2 | Use of uridine in combination with choline for the treatment of memory disorders | Massachusetts Institute of Technology (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2007089703-A2 | METHODS AND COMPOSITIONS FOR AMELIORATING OR INHIBITING DECLINE IN MEMORY OR INTELLIGENCE OR IMPROVING SAME | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-08-09 | — | — | WO | claimed |
| US-20060241077-A1 | Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-10-26 | — | — | US | claimed |
| JP-2003517437-A | — | — | 2003-05-27 | — | — | JP | claimed |
| US-20020028787-A1 | Nervous system disorders; administering exogenous uridine compound | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-03-07 | — | — | US | claimed |
| EP-1140104-A1 | METHODS FOR INCREASING CYTIDINE LEVELS IN VIVO AND TREATING CYTIDINE-DEPENDENT HUMAN DISEASES | Massachusetts Institute of Technology (US) | 2001-10-10 | — | — | EP | claimed |
| EP-0331948-B1 | PHARMACEUTICAL COMPOSITION FOR THE TRANSDERMAL ADMINISTRATION OF HEPARIN | SCHUR PHARMAZEUTIKA GMBH & CO KG (DE) | 1992-01-15 | — | — | EP | claimed |
| EP-0331948-A2 | Pharmaceutical composition for the transdermal administration of heparin | SCHUR PHARMAZEUTIKA GMBH & CO KG (DE) | 1989-09-13 | — | — | EP | claimed |