Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405907 | 0.96 | HTT (0.36) | HTTKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL8405708 | 0.92 | HTT (0.38) | HTTTHRATHRBPLA2G2AKDM4E | |
| SCHEMBL8405371 | 0.90 | HTT (0.36) | HTTTHRATHRBPLA2G2AKDM4E | |
| SCHEMBL8408769 | 0.90 | HTT (0.37) | HTTTHRATHRBKDM4EALDH1A1 | |
| SCHEMBL8408512 | 0.89 | HTT (0.36) | HTTTHRATHRBPLA2G2AKDM4E | |
| SCHEMBL7632961 | 0.89 | HTT (0.36) | HTTTHRATHRBPLA2G2AKDM4E | |
| SCHEMBL8406003 | 0.89 | HTT (0.37) | HTTKDM4EALDH1A1MCL1 | |
| SCHEMBL8408736 | 0.89 | HTT (0.39) | HTTTHRATHRBKDM4EALDH1A1 | |
| SCHEMBL8407349 | 0.88 | HTT (0.35) | HTTTHRATHRBPLA2G2AKDM4E | |
| SCHEMBL7977565 | 0.88 | HTT (0.35) | HTTTHRATHRBPLA2G2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |