SCHEMBL8409223

SCHEMBL8409223

CC(C)c1cc(OCC=C(Cl)Cl)cc(C(C)C)c1OCCCCCl

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
GLRA1 P23415 1/20 0.34
RXRA P19793 2/20 0.31
PPARG P37231 2/20 0.31
RARG P13631 1/20 0.31
RARA P10276 1/20 0.30
RARB P10826 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408524 0.96 HTT (0.37) HTTGLRA1RXRAPPARGRARG
SCHEMBL8408856 0.92 HTT (0.33) HTT
SCHEMBL8408452 0.90 HTT (0.35) HTTGLRA1RXRAPPARGRARG
SCHEMBL8405483 0.89 GLRA1 (0.35) HTTGLRA1
SCHEMBL8408782 0.89 HTT (0.36) HTTGLRA1RXRAPPARGRARG
SCHEMBL8405669 0.88 HTT (0.34) HTT
SCHEMBL8408875 0.88 GLRA1 (0.31) GLRA1RXRAPPARGRARG
SCHEMBL8405945 0.88 HTT (0.35) HTTGLRA1RXRAPPARGRARG
SCHEMBL8409111 0.86 HTT (0.40) HTTGLRA1
SCHEMBL8407345 0.85 HTT (0.40) HTTGLRA1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed