SCHEMBL8409237

SCHEMBL8409237

F/C(Cl)=C/COc1cc(Cl)c(OCCCCOc2ccc(C(F)(F)F)cc2)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
AOC3 Q16853 1/20 0.40
PPARA Q07869 3/20 0.37
NOS1 P29475 4/20 0.37
RHOC P08134 1/20 0.37
RHOA P61586 1/20 0.37
GRM4 Q14833 1/20 0.36
PPARD Q03181 3/20 0.36
CTDSP1 Q9GZU7 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
LTA4H P09960 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409239 1.00 MAOB (0.40) MAOBAOC3PPARANOS1RHOC
SCHEMBL8412561 0.98 MAOB (0.40) MAOBAOC3PPARANOS1RHOC
SCHEMBL8412565 0.98 MAOB (0.40) MAOBAOC3PPARANOS1RHOC
SCHEMBL8409507 0.92 PPARD (0.38) MAOBAOC3PPARANOS1RHOC
SCHEMBL8409510 0.92 PPARD (0.38) MAOBAOC3PPARANOS1RHOC
SCHEMBL8405597 0.92 MAOB (0.39) MAOBAOC3PPARANOS1RHOC
SCHEMBL8341308 0.90 PPARD (0.38) MAOBAOC3PPARARHOCRHOA
SCHEMBL8341315 0.90 PPARD (0.38) MAOBAOC3PPARARHOCRHOA
SCHEMBL8339294 0.89 MAOB (0.40) MAOBAOC3PPARANOS1RHOC
SCHEMBL8339298 0.89 MAOB (0.40) MAOBAOC3PPARANOS1RHOC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP claimed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP claimed
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed