Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.76 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.76 |
| ▸ | OXTR | P30559 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407921 | 0.93 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL8408008 | 0.93 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL8405841 | 0.89 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL8409229 | 0.89 | AVPR2 (0.66) | AVPR2AVPR1AOXTR | |
| SCHEMBL8409578 | 0.87 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL7335432 | 0.86 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL8406431 | 0.82 | AVPR2 (0.63) | AVPR2AVPR1AOXTR | |
| SCHEMBL8406610 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL8408815 | 0.80 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL7339348 | 0.79 | AVPR2 (0.86) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | claimed |
| US-5968937-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |