Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408745 | 0.96 | TP53 (0.39) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8405401 | 0.92 | HTT (0.38) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8405610 | 0.90 | KDM4E (0.38) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL2345060 | 0.90 | HTT (0.36) | TP53MAPK1HTTMAPTSMN1; SMN2 | |
| SCHEMBL8405459 | 0.89 | KDM4E (0.40) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8407866 | 0.88 | KDM4E (0.36) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8409083 | 0.88 | KDM4E (0.39) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL7977888 | 0.88 | KDM4E (0.36) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8407738 | 0.87 | TP53 (0.40) | TP53MAPK1KDM4EPOLBCYP1A2 | |
| SCHEMBL8407281 | 0.87 | KDM4E (0.38) | TP53MAPK1KDM4EPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |