Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.58 |
| ▸ | HTR6 | P50406 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412358 | 0.97 | HTR2B (0.65) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8409850 | 0.96 | HTR2B (0.63) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8412371 | 0.96 | HTR2B (0.63) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8413765 | 0.88 | HTR2B (0.60) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8413485 | 0.88 | HTR2B (0.60) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8410791 | 0.88 | HTR2B (0.60) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8413668 | 0.87 | HTR2B (0.58) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8413804 | 0.87 | HTR2B (0.58) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8413825 | 0.87 | HTR2B (0.58) | HTR2BPDE4DHRH4HTR6HRH3 | |
| SCHEMBL8410739 | 0.86 | HTR2B (0.65) | HTR2BPDE4DHRH4HTR6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962453-A | HEPATITIS THERAPY | NIPPON SHINYAKU CO. LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0775487-A1 | TRIAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-05-28 | — | — | EP | disclosed |