Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703700 | 0.78 | TACR1 (0.61) | TACR1ALDH1A1PAM | |
| SCHEMBL26896456 | 0.77 | TACR1 (0.47) | TACR1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL20905743 | 0.77 | TACR1 (0.47) | TACR1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11043757 | 0.76 | TSHR (0.59) | TACR1KMT2APAMITGB3ITGA2B | |
| SCHEMBL11043759 | 0.76 | TSHR (0.59) | TACR1KMT2APAMITGB3ITGA2B | |
| SCHEMBL2525910 | 0.76 | TACR1 (0.43) | TACR1LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL26896455 | 0.76 | MME (0.51) | TACR1ALDH1A1PPARGITGB3ITGA2B | |
| SCHEMBL9493909 | 0.75 | TACR1 (0.61) | TACR1ALDH1A1CASP1PAM | |
| SCHEMBL9493914 | 0.75 | TACR1 (0.61) | TACR1ALDH1A1CASP1PAM | |
| SCHEMBL8409365 | 0.74 | TACR1 (0.58) | TACR1LMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |