Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026574 | 0.86 | GAA (0.60) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| SCHEMBL8533124 | 0.86 | GAA (0.60) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| SCHEMBL6929324 | 0.86 | GAA (0.60) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| Hydrochloric Acid SCHEMBL8407992 | 0.84 | GAA (0.63) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| Hydrochloric Acid SCHEMBL8409806 | 0.84 | GAA (0.63) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| Hydrochloric Acid SCHEMBL8027086 | 0.84 | GAA (0.63) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| SCHEMBL207179 | 0.84 | GAA (0.62) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| Hydrochloric Acid SCHEMBL8410665 | 0.82 | GAA (0.65) | GAAMEN1KMT2ASMN1; SMN2TUBB4A | |
| SCHEMBL8411235 | 0.81 | MEN1 (0.40) | GAAMEN1KMT2ASMN1; SMN2PTGS2 | |
| Hydrochloric Acid SCHEMBL8407993 | 0.80 | GAA (0.41) | GAAMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910513-A | PROTECTING THE BODY AGAINST OXIDATIVE STRESS SUCH AS NEURODEGENERATIVE DISEASES, PARKINSON'S DISEASE, CHRONIC INFLAMMATORY CONDITIONS, REINFUSION ISCHAEMIA SYNDROME, THE TOXICITY OF CERTAIN DRUGS SUCH AS CERTAIN XENOBIOTICS | L'OREAL (FR) | 1999-06-08 | — | — | US | disclosed |