Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 10/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412255 | 0.88 | ACE (0.57) | ACETACR1LNPEPCTSLGPR132 | |
| SCHEMBL8408864 | 0.82 | ACE (0.64) | ACETACR1LNPEPCTSLGPR132 | |
| SCHEMBL8411428 | 0.77 | TACR1 (0.57) | ACETACR1LNPEPCTSL | |
| SCHEMBL9266687 | 0.76 | TACR1 (0.86) | TACR1LNPEPIL1RNERAP2ERAP1 | |
| SCHEMBL8412258 | 0.75 | GAA (0.58) | ACELNPEPCTSLGPR132PPARG | |
| SCHEMBL3936012 | 0.74 | ACE (0.72) | ACETACR1LNPEPCTSLGPR132 | |
| SCHEMBL3936009 | 0.74 | ACE (0.72) | ACETACR1LNPEPCTSLGPR132 | |
| SCHEMBL8656506 | 0.74 | ACE (0.63) | ACETACR1CTSLGPR132 | |
| SCHEMBL12729964 | 0.74 | ACE (0.63) | ACETACR1CTSLGPR132 | |
| SCHEMBL7709445 | 0.73 | ACE (0.70) | ACETACR1LNPEPCTSLGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |