Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412292 | 0.83 | TSHR (0.50) | TSHRSRCCETPNPC1CASP3 | |
| SCHEMBL8412882 | 0.81 | TSHR (0.47) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL8409179 | 0.81 | TSHR (0.47) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL27908642 | 0.80 | TSHR (1.00) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL51316 | 0.80 | TSHR (1.00) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL444558 | 0.80 | TSHR (0.75) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL4219700 | 0.79 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL11756554 | 0.79 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| Hydrochloric Acid SCHEMBL10722992 | 0.79 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL9446520 | 0.79 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931085-A1 | PHOSPHORYLATING REAGENTS | The University Court of the University of St. Andrews (GB) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998012201-A1 | PHOSPHORYLATING REAGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 1998-03-26 | — | — | WO | disclosed |