Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25960995 | 0.88 | PPARA (0.49) | PPARGPPARACHRM2CHRM1CHRM3 | |
| SCHEMBL5530316 | 0.86 | CA12 (0.39) | SIGMAR1PPARGPPARACHRM2CHRM1 | |
| SCHEMBL19745618 | 0.84 | CA12 (0.40) | SIGMAR1PPARGPPARACHRM2CHRM1 | |
| SCHEMBL22510017 | 0.84 | HTR2A (0.47) | SIGMAR1 | |
| SCHEMBL2635979 | 0.83 | CYP4F2 (0.50) | PPARGPPARACHRM2CHRM1CHRM3 | |
| SCHEMBL6362546 | 0.83 | TAAR1 (0.58) | IDO1CA12CA1CA9TAAR1 | |
| SCHEMBL15472407 | 0.82 | MAOB (0.47) | BCHECYP4F2CYP4A11 | |
| SCHEMBL12093121 | 0.82 | CA12 (0.38) | SIGMAR1PPARGPPARACHRM2CHRM1 | |
| SCHEMBL14382682 | 0.81 | CA12 (0.42) | IDO1CA12CA1CA9TAAR1 | |
| SCHEMBL29975825 | 0.81 | CA12 (0.42) | BCHECYP4F2CYP4A11IDO1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935597-A2 | DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1999-08-18 | — | — | EP | claimed |
| WO-1998019997-A2 | DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | claimed |