Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413568 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL8413369 | 0.98 | TSHR (0.60) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL8409964 | 0.95 | TSHR (0.55) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL11597311 | 0.88 | TSHR (0.55) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL809847 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL809804 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL303363 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL1867314 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL8158336 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL8413578 | 0.88 | TSHR (0.70) | TSHRALDH1A1CYP3A4TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685500-B1 | Copolymer rubber and method for its production | TOSOH CORP (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5512647-A | CYANO GROUP-CONTAINING ACRYLATES, UNSATURATED NITRILES AND OTHER ETHYLENICALLY UNSATURATED MONOMERS; FUEL OIL AND COLD RESISTANCE | TOSOH CORPORATION (JP) | 1996-04-30 | — | — | US | disclosed |
| EP-0685500-A1 | Copolymer rubber and method for its production | TOSOH CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |