⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636086 | 0.80 | — | — | |
| SCHEMBL11838936 | 0.79 | — | — | |
| SCHEMBL30005854 | 0.77 | — | — | |
| SCHEMBL22997910 | 0.73 | HSP90AA1 (0.55) | — | |
| SCHEMBL1417714 | 0.73 | — | — | |
| SCHEMBL648902 | 0.72 | — | — | |
| SCHEMBL11841058 | 0.72 | — | — | |
| SCHEMBL30223597 | 0.71 | — | — | |
| SCHEMBL11471565 | 0.71 | — | — | |
| SCHEMBL1704415 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512901-B1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-06-23 | — | — | EP | disclosed |
| EP-0591040-B1 | Quaternary basic amides as tachykinines antagonists | SANOFI SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| EP-0474561-B1 | Arylalkylamines, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0515240-B1 | N-(aminoalkyl)piperidine compounds and their enantiomers as neurokinines receptors antagonists, processes for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-09-24 | — | — | EP | disclosed |
| EP-0591040-A1 | Quaternary basic amides as tachykinines antagonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993018002-A1 | QUATERNARY SALTS OF 4-SUBSTITUTED PIPERIDINES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-09-16 | — | — | WO | disclosed |
| EP-0559538-A1 | Quaternary salts of 4-substituted piperidines, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-08 | — | — | EP | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0515240-A1 | N-alkylidene piperidine compounds and their enatiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0512902-A1 | Dialkyleneperidino compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |
| EP-0512901-A1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |
| EP-0474561-A1 | Arylalkylamines, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-03-11 | — | — | EP | disclosed |
| EP-0428434-A2 | Compounds of aromatic amines and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1991-05-22 | — | — | EP | disclosed |
| EP-0375560-A1 | Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1990-06-27 | — | — | EP | disclosed |