Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414253 | 0.88 | PTGIR (0.75) | PTGIRPTGDR | |
| SCHEMBL8411054 | 0.86 | PTGIR (0.59) | PTGIRTBXAS1SIGMAR1PTGDR | |
| SCHEMBL8410742 | 0.85 | PTGIR (0.77) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8414254 | 0.84 | PTGIR (0.56) | PTGIRTBXAS1SIGMAR1PTGDR | |
| SCHEMBL8414340 | 0.83 | PTGIR (0.57) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8414219 | 0.82 | PTGIR (0.66) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8414109 | 0.81 | PTGIR (0.56) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8413360 | 0.80 | PTGIR (0.69) | PTGIRTBXAS1SIGMAR1PTGDR | |
| SCHEMBL8811344 | 0.80 | PTGIR (0.68) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8519034 | 0.80 | PTGIR (0.68) | PTGIRTBXAS1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |