Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 19/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414344 | 0.88 | PTGIR (0.48) | PTGIRTBXAS1 | |
| SCHEMBL8411139 | 0.85 | PTGIR (0.61) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8410974 | 0.84 | PTGIR (0.63) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8414330 | 0.83 | CYP19A1 (0.50) | PTGIR | |
| SCHEMBL8412758 | 0.82 | PTGIR (0.63) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8410703 | 0.82 | PTGIR (0.59) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8810501 | 0.81 | PTGIR (0.55) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8812732 | 0.81 | PTGIR (0.55) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8413612 | 0.79 | PTGIR (0.59) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8414253 | 0.79 | PTGIR (0.75) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |