Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 19/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414349 | 0.88 | PTGIR (0.41) | PTGIRKDM4E | |
| SCHEMBL8411091 | 0.77 | PTGIR (0.61) | PTGIR | |
| SCHEMBL8812035 | 0.76 | PTGIR (0.41) | PTGIR | |
| SCHEMBL8811804 | 0.76 | PTGIR (0.41) | PTGIR | |
| SCHEMBL8412741 | 0.75 | PTGIR (0.58) | PTGIRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8414332 | 0.75 | PTGIR (0.59) | PTGIRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8815165 | 0.75 | PTGIR (0.52) | PTGIR | |
| SCHEMBL8815160 | 0.75 | PTGIR (0.52) | PTGIR | |
| SCHEMBL8414250 | 0.73 | PTGIR (0.73) | PTGIR | |
| SCHEMBL7778750 | 0.73 | PTGIR (0.65) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |