Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410716 | 0.92 | PTGIR (0.45) | PTGIRTBXAS1CYP19A1 | |
| SCHEMBL8812663 | 0.91 | PTGIR (0.44) | PTGIRTBXAS1CYP19A1MTNR1AMTNR1B | |
| SCHEMBL8414348 | 0.87 | PTGIR (0.60) | PTGIRTBXAS1 | |
| SCHEMBL8410714 | 0.87 | PTGIR (0.51) | PTGIRTBXAS1 | |
| SCHEMBL8413614 | 0.83 | PTGIR (0.45) | PTGIRTBXAS1CYP19A1MTNR1AMTNR1B | |
| SCHEMBL8411141 | 0.83 | PTGIR (0.46) | PTGIRTBXAS1CYP19A1MTNR1AMTNR1B | |
| SCHEMBL8412761 | 0.79 | PTGIR (0.48) | PTGIRTBXAS1CYP19A1MTNR1AMTNR1B | |
| SCHEMBL8410707 | 0.79 | PTGIR (0.45) | PTGIRTBXAS1CYP19A1 | |
| SCHEMBL8411093 | 0.79 | PTGIR (0.46) | PTGIRTBXAS1MTNR1AMTNR1B | |
| SCHEMBL8413478 | 0.79 | PTGIR (0.44) | PTGIRTBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |