Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.70 |
| ▸ | CFTR | P13569 | 2/20 | 0.70 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375241 | 0.88 | AKT2 (0.48) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL6476580 | 0.84 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| Ammonia Solution, Strong SCHEMBL6000375 | 0.82 | SLC6A2 (0.95) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL13089180 | 0.71 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL3070057 | 0.70 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL6532251 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EAKT2AKT1 | |
| SCHEMBL16156937 | 0.69 | AKT2 (0.45) | KMT2AAKT2AKT1KCNH2 | |
| SCHEMBL7999525 | 0.69 | AKT2 (0.50) | ALDH1A1KDM4EAKT2AKT1 | |
| SCHEMBL17875272 | 0.69 | AKT2 (0.47) | AKT2AKT1 | |
| SCHEMBL10674497 | 0.69 | CYP19A1 (1.00) | SLC6A2SLC6A4SLC6A3CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |