Adenine

Adenine

SCHEMBL8414752

NC(=O)c1cccnc1.Nc1ncnc2[nH]cnc12.c1ccncc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.52
F3 P13726 1/20 0.52
SARM1 Q6SZW1 1/20 0.52
SIRT2 Q8IXJ6 1/20 0.52
SIRT6 Q8N6T7 1/20 0.52
SIRT1 Q96EB6 1/20 0.52
SIRT3 Q9NTG7 1/20 0.52
SIRT5 Q9NXA8 1/20 0.52
SIRT4 Q9Y6E7 1/20 0.52
EGFR P00533 1/20 0.45
SRC P12931 1/20 0.45
KDR P35968 1/20 0.45
ALDH1A1 P00352 2/20 0.40
APP P05067 1/20 0.40
GAA P10253 1/20 0.40
HCAR3 P49019 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
CCNA2 P20248 2/20 0.39
CDK2 P24941 2/20 0.39
PLOD2 O00469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL9274696 0.96 F7 (0.54) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL2564207 0.96 F7 (0.56) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL15699 0.96 F7 (0.56) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL22748483 0.96 F7 (0.56) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL23859925 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL22129922 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL7712105 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL23531099 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL11807677 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6
Adenine SCHEMBL28614873 0.95 F7 (0.55) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968766-A Method and apparatus for sensing the presence of microbes B.E. SAFE (US) 1999-10-19 US claimed
EP-0902888-A1 METHOD AND APPARATUS FOR SENSING THE PRESENCE OF MICROBES B-E Safe, Inc. (US) 1999-03-24 EP claimed
US-5760406-A Method and apparatus for sensing the presence of microbes MICROBIOSYSTEMS, LP 1998-06-02 US claimed
WO-1997046867-A1 METHOD AND APPARATUS FOR SENSING THE PRESENCE OF MICROBES B-E SAFE, INC. (US) 1997-12-11 WO claimed