⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24583876 | 1.00 | — | — | |
| SCHEMBL24584575 | 1.00 | — | — | |
| SCHEMBL24584579 | 1.00 | — | — | |
| SCHEMBL24583829 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29739764 | 0.97 | MEN1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL27193624 | 0.97 | MEN1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL27193626 | 0.97 | MEN1 (0.46) | — | |
| SCHEMBL330879 | 0.77 | — | — | |
| SCHEMBL8202573 | 0.77 | — | — | |
| SCHEMBL24268905 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081363-A1 | COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | Revolution Medicines, Inc. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2023018648-A1 | PHENOL DERIVATIVES FOR USE IN THE MODULATION OF BRM | GENENTECH, INC. (US) | 2023-02-16 | — | — | WO | disclosed |
| EP-0938492-A1 | COMBINATORIAL SYNTHESIS OF CARBOHYDRATE LIBRARIES | SYNSORB Biotech Inc. (CA) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998022487-A1 | COMBINATORIAL SYNTHESIS OF CARBOHYDRATE LIBRARIES | SYNSORB BIOTECH, INC. (CA) | 1998-05-28 | — | — | WO | disclosed |