SCHEMBL84159

SCHEMBL84159

NC[C@H](F)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3439164 1.00
SCHEMBL988689 1.00
Hydrochloric Acid SCHEMBL25318862 0.96
Hydrochloric Acid SCHEMBL25235322 0.96
SCHEMBL4014867 0.79
SCHEMBL2382246 0.79
Hydrochloric Acid SCHEMBL9847517 0.75
Hydrochloric Acid SCHEMBL31268132 0.75
SCHEMBL30069079 0.72
SCHEMBL19343233 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034176-B2 Aminopropylphosphinic acids ASTRAZENECA AB (SE) 2006-04-25 US claimed
US-20050137414-A1 New aminopropylphosphinic acids ELEBRING THOMAS (SE) 2005-06-23 US claimed
US-20030220303-A1 New aminopropylphosphinic acids ELEBRING THOMAS (SE) 2003-11-27 US claimed
US-6596711-B1 GABA B receptor agonists for use in the treatment of CNS disorders, such as muscle relaxation in spinal spasticity, cardiovascular disorders, asthma, gut motility disorders such as irritable bowel syndrome and gastroesophogeal reflux ASTRAZENECA AB (SE) 2003-07-22 US claimed
CN-1413104-A New (aminopropyl) methylphosphinic acids ASTRAZENECA AB (SE) 2003-04-23 CN claimed
CN-1409716-A New amino propylphosphinic acid ASTRAZENECA AB (SE) 2003-04-09 CN claimed
US-20020156053-A1 New aminopropylphosphinic acids GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-10-24 US claimed
CN-117886824-B 2, 3-Dihydropyrimido [4,5-d ] pyrimidine-4 (1H) -ketone derivative, preparation method and application thereof 四川大学华西医院 2026-05-15 CN disclosed
EP-4688161-A1 IL4I1 INHIBITORS AND METHODS OF USE Merck Sharp & Dohme LLC (US) 2026-02-11 EP disclosed
EP-4658662-A1 MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS Yuhan Corporation (KR) 2025-12-10 EP disclosed
EP-4655304-A1 MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS Yuhan Corporation (KR) 2025-12-03 EP disclosed
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
EP-4617273-A1 FUSED TRICYCLIC PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Haihe Biopharma Co., Ltd. (CN) 2025-09-17 EP disclosed
CN-1413104-A New (aminopropyl) methylphosphinic acids ASTRAZENECA AB (SE) 2003-04-23 CN disclosed
CN-1409716-A New amino propylphosphinic acid ASTRAZENECA AB (SE) 2003-04-09 CN disclosed
US-20020156053-A1 New aminopropylphosphinic acids GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-10-24 US disclosed
EP-1239843-A1 NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS AstraZeneca AB (SE) 2002-09-18 EP disclosed
EP-1240172-A1 NEW AMINOPROPYLPHOSPHINIC ACIDS AstraZeneca AB (SE) 2002-09-18 EP disclosed
WO-2001042252-A1 NEW AMINOPROPYLPHOSPHINIC ACIDS ASTRAZENECA AB (SE) 2001-06-14 WO disclosed
WO-2001041743-A1 NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS ASTRAZENECA AB (SE) 2001-06-14 WO disclosed