Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415928 | 1.00 | GRIA1 (0.39) | GRIA1GRIA2GRIA3MEN1KMT2A | |
| SCHEMBL8076417 | 0.90 | GRIA1 (0.41) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8076415 | 0.90 | GRIA1 (0.41) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL7767225 | 0.89 | GRIA1 (0.40) | GRIA1GRIA2GRIA3MEN1KMT2A | |
| SCHEMBL8083751 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8084477 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8083750 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8076424 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8084479 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR | |
| SCHEMBL8076422 | 0.89 | TSHR (0.42) | GRIA1GRIA2GRIA3SPHK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |