SCHEMBL8415992

SCHEMBL8415992

NC1CCC(C(O)C(=O)O)CC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
CPB2 Q96IY4 1/20 0.32
SLC1A2 P43004 2/20 0.30
SLC1A1 P43005 2/20 0.30
ALOX5 P09917 1/20 0.30
SMYD3 Q9H7B4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16815070 0.87
SCHEMBL10955186 0.87
SCHEMBL23673345 0.87
SCHEMBL22081716 0.81 EPHX1 (0.38) DPP4ALOX5SMYD3
SCHEMBL22081717 0.81 EPHX1 (0.38) DPP4ALOX5SMYD3
SCHEMBL22081715 0.81 EPHX1 (0.38) DPP4ALOX5SMYD3
SCHEMBL22081098 0.81 EPHX1 (0.38) DPP4ALOX5SMYD3
SCHEMBL24355136 0.79 DPP4 (0.35) DPP4ALOX5SMYD3
SCHEMBL24355685 0.79 DPP4 (0.35) DPP4ALOX5SMYD3
SCHEMBL24355684 0.79 DPP4 (0.35) DPP4ALOX5SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880284-A HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS DR. KARL THOMAE GMBH (DE) 1999-03-09 US disclosed
US-5681841-A PREVENTION CELL AGGREGATION KARL THOMAE GMBH (DE) 1997-10-28 US disclosed