SCHEMBL8416342

SCHEMBL8416342

C=C(C)C(N)=O.O=CC=O

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.75
LMNA P02545 1/20 0.41
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
ALDH1A1 P00352 5/20 0.35
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
HSD17B10 Q99714 1/20 0.30
CRBN Q96SW2 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrolein SCHEMBL11656965 0.88 TDP1 (0.67) TDP1LMNAALOX15BLMPMP22
Formic Acid SCHEMBL20943274 0.88
Acetaldehyde SCHEMBL28054939 0.88
SCHEMBL14870 0.87
SCHEMBL2128293 0.87 TDP1 (1.00) TDP1LMNAALOX15BLMPMP22
SCHEMBL5708652 0.87 TDP1 (1.00) TDP1LMNAALOX15BLMPMP22
SCHEMBL713567 0.85 TDP1 (0.71) TDP1LMNAALOX15BLMPMP22
Ammonia Solution, Strong SCHEMBL7618993 0.83 TDP1 (0.92) TDP1LMNAALOX15BLMPMP22
Hydrogen Sulfide SCHEMBL8940298 0.83
Bromide SCHEMBL270286 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112111795-B Preparation method of one-step nanofiber hydrogel 浙江理工大学 2021-11-23 CN claimed
CN-112111795-A Preparation device and method of one-step method nanofiber hydrogel 浙江理工大学 2020-12-22 CN claimed
CN-112111795-B Preparation method of one-step nanofiber hydrogel 浙江理工大学 2021-11-23 CN disclosed
CN-112111795-A Preparation device and method of one-step method nanofiber hydrogel 浙江理工大学 2020-12-22 CN disclosed
EP-0528537-B1 Aqueous crosslinked polymer particles and their production; aqueous dispersions containing same; and use in aqueous paints NIPPON PAINT CO LTD (JP) 1999-09-08 EP disclosed
US-5536771-A PAINT WORKABILITY NIPPON PAINT CO., LTD. (JP) 1996-07-16 US disclosed
EP-0528537-A1 Aqueous crosslinked polymer particles and their production; aqueous dispersions containing same; and use in aqueous paints Nippon Paint Co., Ltd. (JP) 1993-02-24 EP disclosed