2-Oxoisovalerate

2-Oxoisovalerate

SCHEMBL8417263

CC(C)C(=O)C(=O)O.CC(C)[C@H](N)C(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.71
SLC1A3 P43003 2/20 0.38
SLC1A2 P43004 2/20 0.38
SLC1A1 P43005 2/20 0.38
DPP4 P27487 2/20 0.33
TP53 P04637 1/20 0.33
FAP Q12884 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
GRIK1 P39086 3/20 0.32
GRIK2 Q13002 2/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
LAP3 P28838 1/20 0.32
GRIA2 P42262 2/20 0.31
GRIA4 P48058 2/20 0.31
GRIK3 Q13003 2/20 0.31
GRIK5 Q16478 2/20 0.31
GRIA1 P42261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Oxoisovalerate SCHEMBL8417262 1.00 SLC7A5 (0.71) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
2-Oxoisovalerate SCHEMBL22070188 1.00 SLC7A5 (0.71) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL2339837 0.85 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL7015574 0.85 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL7015567 0.85 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL2785563 0.84 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL41225 0.84 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL8516 0.84
Valine SCHEMBL1813972 0.84 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL288203 0.84 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604774-B2 Production of renewable hydrocarbon compositions BUTAMAX ADVANCED BIOFUELS LLC (US) 2020-03-31 US disclosed
US-20180066290-A1 Production of Renewable Hydrocarbon Compositions GEVO, INC. 2018-03-08 US disclosed
US-9840724-B2 Production of renewable hydrocarbon compositions BUTAMAX ADVANCED BIOFUELS LLC (US) 2017-12-12 US disclosed
US-20150240267-A1 PRODUCTION OF RENEWABLE HYDROCARBON COMPOSITIONS GEVO, INC. 2015-08-27 US disclosed
WO-2014047421-A1 PRODUCTION OF RENEWABLE HYDROCARBON COMPOSITIONS BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) 2014-03-27 WO disclosed
EP-0937156-A2 PREPARATION OF D-AMINO ACIDS BY DIRECT FERMENTATIVE MEANS MONSANTO COMPANY (US) 1999-08-25 EP disclosed
WO-1998014602-A2 PREPARATION OF D-AMINO ACIDS BY DIRECT FERMENTATIVE MEANS NSC TECHNOLOGIES LLC (US) 1998-04-09 WO disclosed
WO-1988001836-A1 COHESIVE VEGETABLE PRODUCTS AND PROCESS FOR MANUFACTURE COX JAMES P (US) 1988-03-24 WO disclosed