Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.33 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417785 | 1.00 | FGFR2 (0.38) | FGFR2LRRK2GRM1ALPLCYP1A2 | |
| SCHEMBL8415011 | 0.84 | NSD2 (0.38) | FGFR2LRRK2GRM1CYP2D6CYP2C19 | |
| SCHEMBL8415010 | 0.84 | NSD2 (0.38) | FGFR2LRRK2GRM1CYP2D6CYP2C19 | |
| SCHEMBL8414953 | 0.83 | NSD2 (0.39) | FGFR2LRRK2GRM1ALPLCYP1A2 | |
| SCHEMBL8414952 | 0.83 | NSD2 (0.39) | FGFR2LRRK2GRM1ALPLCYP1A2 | |
| SCHEMBL8416212 | 0.82 | NSD2 (0.37) | FGFR2LRRK2GRM1ALPLNSD2 | |
| SCHEMBL8416572 | 0.82 | FGFR2 (0.43) | FGFR2LRRK2GRM1NSD2KMT5B | |
| SCHEMBL8415175 | 0.82 | NSD2 (0.37) | FGFR2LRRK2GRM1ALPLNSD2 | |
| SCHEMBL8415176 | 0.82 | NSD2 (0.37) | FGFR2LRRK2GRM1ALPLNSD2 | |
| SCHEMBL8416576 | 0.82 | FGFR2 (0.43) | FGFR2LRRK2GRM1NSD2KMT5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877322-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0719257-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007892-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |