SCHEMBL841786

SCHEMBL841786

[O]C1CCCOO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19100153 0.92
SCHEMBL28076178 0.89
SCHEMBL1059967 0.81
SCHEMBL8207346 0.69
SCHEMBL22804154 0.69
SCHEMBL7390 0.69
SCHEMBL9331560 0.65
SCHEMBL7129634 0.65
SCHEMBL6342933 0.65
SCHEMBL7570146 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143408-B2 N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain ASTRAZENECA AB (SE) 2012-03-27 US claimed
US-20100137322-A1 NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN ASTRAZENECA AB (SE) 2010-06-03 US claimed
EP-2158198-A2 NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN AstraZeneca AB (SE) 2010-03-03 EP claimed
WO-2008130320-A2 NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN ASTRAZENECA AB (SE) 2008-10-30 WO claimed
WO-2024143336-A1 HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT 日本曹達株式会社 2024-07-04 WO disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
CN-117693500-A Carboxamide derivative and agricultural/horticultural plant disease control agent 组合化学工业株式会社 2024-03-12 CN disclosed
WO-2023132369-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT 中外製薬株式会社 2023-07-13 WO disclosed
WO-2023286855-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT クミアイ化学工業株式会社 2023-01-19 WO disclosed
US-20210346337-A1 ANTICANCER ROCAGLAMIDE DERIVATIVES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-11-11 US disclosed
EP-3863625-A1 ANTICANCER ROCAGLAMIDE DERIVATIVES The Research Institute at Nationwide Children's Hospital (US) 2021-08-18 EP disclosed
CN-106554382-B Application in nucleoside phosphoramidite class compound and preparation method thereof and drug 四川科伦博泰生物医药股份有限公司 2019-12-03 CN disclosed
EP-1569928-A1 THERAPEUTIC COMPOUNDS AND METHODS The Government of the State of Sarawak, Malaysia (MY) 2005-09-07 EP disclosed
EP-1303520-A4 THERAPEUTIC COMPOUNDS AND METHODS GOVERNMENT OF THE STATE OF SAR (MY) 2005-03-30 EP disclosed
WO-2004041812-A1 THERAPEUTIC COMPOUNDS AND METHODS THE GOVERNMENT OF THE STATE OF SARAWAK, MALAYSIA (MY) 2004-05-21 WO disclosed
US-6710075-B2 COMPOUNDS HAVING A CYCLOPENTABENZOFURAN CORE SHOWN TO EXHIBIT POTENT CYTOTOXIC AND CYTOSTATIC EFFECTS ON CANCER CELL GROWTH AND VIABILITY THE GOVERNMENT OF THE STATE OF SARAWAK, MALAYSIA (MY) 2004-03-23 US disclosed
US-20030181514-A1 Therapeutic compounds and methods GOVERNMENT OF THE STATE OF SARAWAK, MALAYSIA (MY) 2003-09-25 US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
EP-1303520-A1 THERAPEUTIC COMPOUNDS AND METHODS The Government of the State of Sarawak, Malaysia (MY) 2003-04-23 EP disclosed
WO-2002002566-A1 THERAPEUTIC COMPOUNDS AND METHODS THE GOVERNMENT OF THE STATE OF SARAWAK, MALAYSIA (MY) 2002-01-10 WO disclosed