Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.81 |
| ▸ | YES1 | P07947 | 2/20 | 0.81 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417865 | 1.00 | SRC (0.81) | SRCYES1GRB2 | |
| SCHEMBL8418266 | 0.91 | SRC (0.81) | SRCYES1GRB2 | |
| SCHEMBL8418270 | 0.91 | SRC (0.81) | SRCYES1GRB2 | |
| SCHEMBL8419356 | 0.90 | SRC (1.00) | SRCYES1 | |
| SCHEMBL8419359 | 0.90 | SRC (1.00) | SRCYES1 | |
| SCHEMBL7221405 | 0.83 | SRC (0.86) | SRCYES1 | |
| SCHEMBL7220784 | 0.82 | SRC (0.86) | SRCYES1 | |
| SCHEMBL8419505 | 0.81 | SRC (0.85) | SRCYES1 | |
| SCHEMBL8419506 | 0.81 | SRC (0.85) | SRCYES1 | |
| SCHEMBL7221403 | 0.81 | SRC (1.00) | SRCYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |