Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.54 |
| ▸ | HRH1 | P35367 | 9/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917513 | 0.84 | HRH3 (0.51) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL16418028 | 0.83 | HRH3 (0.50) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL8810717 | 0.82 | CNR2 (0.56) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917454 | 0.82 | HRH3 (0.49) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917446 | 0.82 | HRH3 (0.49) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917448 | 0.82 | HRH3 (0.62) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917502 | 0.82 | HRH3 (0.62) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917447 | 0.82 | HRH3 (0.52) | ADRA1AHRH3HRH1ADRA1BKCNH2 | |
| SCHEMBL9917532 | 0.81 | HRH3 (0.53) | ADRA1AHRH3KCNH2ADRA2ACHRM2 | |
| SCHEMBL9917449 | 0.81 | HRH3 (0.54) | ADRA1AHRH3HRH1ADRA1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |