Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759574 | 1.00 | CYP2C9 (0.36) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL8394968 | 1.00 | CYP2C9 (0.36) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7759571 | 1.00 | CYP2C9 (0.36) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7753093 | 0.89 | CYP2C9 (0.37) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7753091 | 0.89 | CYP2C9 (0.37) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7754844 | 0.89 | CYP2C9 (0.37) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL8858365 | 0.89 | CYP2C9 (0.37) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL8415888 | 0.86 | CYP2C9 (0.35) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7757728 | 0.86 | CYP2C9 (0.35) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7757723 | 0.86 | CYP2C9 (0.35) | CYP2C9ESR2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |