Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800085 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL29263637 | 0.85 | KMT2A (0.51) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL6536709 | 0.85 | PRSS1 (0.51) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL23174851 | 0.84 | KMT2A (0.58) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL689043 | 0.84 | KMT2A (0.63) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL419283 | 0.82 | KMT2A (0.53) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL689052 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL688997 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL27465955 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL17157057 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-4710549-A | Cross-linked phosphazene polymer | ETHYL CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |