Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.60 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667982 | 0.81 | POLB (0.52) | CA2CA1CA9POLBCYP2C9 | |
| SCHEMBL7115130 | 0.81 | POLB (0.47) | CA2CA1CA9POLBALDH1A1 | |
| SCHEMBL29786464 | 0.80 | CA1 (0.64) | CA2CA1CA9CA4CA6 | |
| SCHEMBL3922877 | 0.78 | CA1 (0.62) | CA2CA1CA9CA4CA6 | |
| SCHEMBL16467622 | 0.78 | POLB (0.44) | CA2CA1CA9POLBCYP2C9 | |
| SCHEMBL5145547 | 0.77 | CA1 (0.60) | CA2CA1CA9LDHACA12 | |
| SCHEMBL18095563 | 0.77 | CA1 (0.60) | CA2CA1CA9CA4CA6 | |
| SCHEMBL1806305 | 0.77 | CA1 (0.60) | CA2CA1CA9CA4CA6 | |
| SCHEMBL1806301 | 0.77 | CA1 (0.60) | CA2CA1CA9CA4CA6 | |
| SCHEMBL16467623 | 0.77 | POLB (0.43) | CA2CA1CA9POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942752-A1 | ANTICONVULSANT CONTAINING COMPOSITION FOR TREATING NEUROPATHIC PAIN | Algos Pharmaceutical Corporation (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998007447-A1 | ANTICONVULSANT CONTAINING COMPOSITION FOR TREATING NEUROPATHIC PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-02-26 | — | — | WO | disclosed |