Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582884 | 0.72 | MAPK14 (0.74) | MAPK14MAPK11MAPK13MAPK12MAPK9 | |
| SCHEMBL5639818 | 0.71 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12CSNK1E | |
| SCHEMBL1639908 | 0.71 | MAPK14 (0.50) | MAPK14MAPK11MAPK13MAPK12MAPK9 | |
| SCHEMBL7608455 | 0.70 | MAPK14 (0.75) | MAPK14MAPK11MAPK13MAPK12MAPK9 | |
| SCHEMBL8418263 | 0.69 | MAPK14 (0.53) | MAPK14MAPK11MAPK13MAPK12MAPK9 | |
| SCHEMBL1640808 | 0.65 | CSNK1D (0.45) | MAPK14MAPK9MAP4K4EGFRFRK | |
| SCHEMBL4916626 | 0.65 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12MAPK9 | |
| SCHEMBL5095719 | 0.64 | MAPK14 (0.59) | MAPK14MAPK11MAPK13MAPK12CSNK1A1 | |
| SCHEMBL2851563 | 0.64 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12MAPK10 | |
| SCHEMBL4601388 | 0.64 | MAPK14 (0.45) | MAPK14MAPK11MAPK13MAPK12MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917043-A | INTERMEDIATES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |