Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602250 | 0.93 | TSHR (0.64) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL8767950 | 0.89 | TSHR (0.60) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL28238018 | 0.87 | TSHR (1.00) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL50039 | 0.87 | TSHR (1.00) | TSHRLMNAALDH1A1MGAMGAA | |
| Acetic Acid SCHEMBL28197982 | 0.84 | TSHR (0.83) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL8069375 | 0.84 | TSHR (0.94) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL8582764 | 0.84 | TSHR (0.94) | TSHRLMNAALDH1A1MGAMGAA | |
| Dimethyl Succinate SCHEMBL7262656 | 0.84 | TSHR (0.94) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL8584321 | 0.84 | TSHR (0.94) | TSHRLMNAALDH1A1MGAMGAA | |
| SCHEMBL6629340 | 0.84 | TSHR (0.94) | TSHRLMNAALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |